Background: Prenatal multiple micronutrient supplementation (MMS), in comparison to iron and folic acid supplementation (IFA), improves pregnancy outcomes, but less is known about their effect on infant growth. Objectives: We conducted a systematic review of trials comparing maternal MMS to IFA and assessed the effect on infants’ anthropometric outcomes at birth, 3, 6, 12, 18, and 24 mo of age. Methods: We included trials from a Cochrane review and new studies identified through systematic literature searches in 3 databases. We calculated the pooled effect estimates with 95% confidence intervals (CIs) using a generic inverse variance method, with fixed (primary analysis) and random-effects, and assessed subgroup differences.